HIV molecular transmission networks among students in Guangxi: unraveling the dynamics of student-driven HIV epidemic.

ABSTRACT: In Guangxi, the number of newly diagnosed HIV-1 infections among students is continuously increasing, highlighting the need for a detailed understanding of local transmission dynamics, particularly focusing on key drivers of transmission. We recruited individuals newly diagnosed with HIV-1 in Nanning, Guangxi, and amplified and sequenced the HIV-1 pol gene to construct a molecular network. Bayesian phylogenetic analysis was utilized to identify migration events, and multivariable logistic regression was employed to analyze factors influencing clustering and high linkage. The predominant subtype among students was CRF07_BC (58.5%), followed by CRF01_AE (17.4%) and CRF55_01B (13.5%). Transmission network analysis identified a significant clustering rate of 64.3% among students, primarily wit

SUBMITTER: Pang X 

PROVIDER: S-EPMC11809174 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature