Incidence and Survival of Children and Adolescents With Wilms Tumor, United States, 2001-2020.

ABSTRACT:

Background

Wilms tumor (WT) is the most common pediatric malignancy of the kidney. Past studies describing WT incidence and survival used surveillance data with < 30% of the US population. We evaluated differences in WT incidence and survival comparing demographic groups and tumor characteristics.

Methods

We analyzed new cases of WT among patients aged < 20 years at diagnosis by using incidence data from US Cancer Statistics (USCS) for 2003-2020 and 5-year relative survival (RS) data from the National Program of Cancer Registries (NPCR) for 2001-2019. To assess incidence trends, average annual percent change (AAPC) was calculated by using joinpoint regression. Relative survival (RS) and all-cause survival were calculated overall and by demographic and clinical variables.

SUBMITTER: Espinoza AF 

PROVIDER: S-EPMC11809554 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature