Factors influencing sepsis associated thrombocytopenia (SAT): A multicenter retrospective cohort study.

ABSTRACT:

Introduction

Sepsis associated thrombocytopenia (SAT) is a common complication of sepsis. We designed this study to investigate factors influencing SAT.

Methods

Patients with sepsis (2984 in Peking union medical college hospital [PUMCH] database, 13165 in eICU Collaborative Research [eICU] database, 11101 in Medical Information Mart for Intensive Care IV [MIMIC-IV] database) were enrolled. Variables included basic information, comorbidities, and organ functions. Multi-variable logistic regression models and artificial neural network model were applied to determine the factors related to SAT.

Main results

Age and body mass index (BMI) were inversely correlated with the incidence of SAT (p-value 0.175 and 0.049 [PUMCH], p-value 0.000 and 0.000 [eICU], p-value 0.000 and

SUBMITTER: Wang L 

PROVIDER: S-EPMC11809783 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature