Serologic Responses to COVID-19 Vaccination in Pediatric Kidney Transplant Recipients.

ABSTRACT:

Background

There are limited data describing the immune responses to COVID-19 vaccination in pediatric kidney transplant recipients, and expanding upon this information could help inform vaccination strategies in this unique population.

Methods

We performed a prospective, observational, single-center cohort study using remnant blood samples of pediatric kidney transplant recipients from routine clinic visits to examine longitudinal serological responses after COVID-19 vaccination. We enrolled 61 pediatric kidney transplant recipients who had at least 1 sample available for analysis. Sera or plasma were analyzed for ancestral SARS-CoV-2 and Omicron (B.1.1.529; BA.1) spike IgG and nucleocapsid IgG using a Meso Scale Discovery platform.

Results

One month after a 3-dose C

SUBMITTER: Goggin KP 

PROVIDER: S-EPMC11809963 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature