Moculus: an immersive virtual reality system for mice incorporating stereo vision.

ABSTRACT: Due to technical roadblocks, it is unclear how visual circuits represent multiple features or how behaviorally relevant representations are selected for long-term memory. Here we developed Moculus, a head-mounted virtual reality platform for mice that covers the entire visual field, and allows binocular depth perception and full visual immersion. This controllable environment, with three-dimensional (3D) corridors and 3D objects, in combination with 3D acousto-optical imaging, affords rapid visual learning and the uncovering of circuit substrates in one measurement session. Both the control and reinforcement-associated visual cue coding neuronal assemblies are transiently expanded by reinforcement feedback to near-saturation levels. This increases computational capability and allows compet

SUBMITTER: Judak L 

PROVIDER: S-EPMC11810792 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature