A Canadian multicenter pediatric eosinophilic esophagitis cohort: Evidence for a nondilation approach to esophageal narrowing.

ABSTRACT:

Objectives

Improving characterization of the narrowing phenotype in pediatric eosinophilic esophagitis (EoE).

Methods

New pediatric EoE diagnoses from 2015 to 2018 were retrospectively identified in Vancouver (BC), Northern Alberta (AB), Hamilton (ON), and Nova Scotia (NS). Incidence rates were calculated using 2016 Federal census data. Clinical, endoscopic, and histologic data were gathered from diagnosis until the end of the follow-up period (fall 2019).

Results

The incidence of EoE in patients less than 15 years old was 5.4 per 100,000 person-years. Of the 332 new diagnoses, 40 (12.0%) had endoscopically identified esophageal narrowing at diagnosis or during the follow-up period, with a subset of 11 (27.5% of narrowed cohort) patients undergoing mechanical esophage

SUBMITTER: Burnett D 

PROVIDER: S-EPMC11810807 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature