Ecological complexity of zoonotic malaria in macaque natural hosts.

ABSTRACT: Macaques are important reservoirs of zoonotic malaria in Southeast Asia. Although cross-sectional malaria surveys have been conducted in macaques, little is known about intra-host infection dynamics and host variation in susceptibility to infection in these infectious reservoirs. We performed a longitudinal monitoring of Plasmodium and Hepatocystis infections by microscopy, species-specific polymerase chain reaction (PCR) and targeted amplicon deep sequencing (TADS) in three long-tailed macaques and 20 pig-tailed macaques in two districts of Narathiwat Province, southern Thailand. In total, 104 macaques' blood samples were obtained during 5 visits with sequential time intervals of 9, 4, 7 and 12 months. Transiently patent Plasmodium infections with low parasite density ( ≤ 1,050 parasites/

SUBMITTER: Putaporntip C 

PROVIDER: S-EPMC11810990 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature