Wound Coverage, Adjuvant Treatments, and Surgical Outcomes for Major Keloid Scars: A Systematic Review and Meta-Analysis.

ABSTRACT: Patients suffering from keloid scarring often face debilitating functional and psychosocial symptoms. The complex pathophysiology of keloids necessitates a patient-centered therapeutic regimen to optimize patient satisfaction and disease resolution. This is especially challenging for patients with major keloid scars that once surgically resected, leave a defect that cannot be closed primarily. The authors intended to identify existing therapeutic regimens reported for the treatment of major keloids and detail the clinical and patient-satisfaction outcomes for those approaches. A systematic review and meta-analysis was designed in accordance with Preferred Reporting Items for Systematic reviews and Meta-analyses guidelines, querying 2 databases along with a manual search for relevant litera

SUBMITTER: Cardenas D 

PROVIDER: S-EPMC11811037 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature