Antiviral defence arsenal across members of the Bacillus cereus group.

ABSTRACT: Bacteria co-evolve with bacteriophages to overcome each other's defence arsenal. Bacillus cereus group gathers bacteria of medical and agricultural importance, including foodborne pathogens. So far, few studies have portrayed a complete defence arsenal of microorganisms, and the role of antiviral systems in the Bacillus cereus group has been overlooked. Here, we investigate the repertoire of defence systems in 6354 B. cereus group's genomic assemblies, using bioinformatics tools DefenseFinder and PADLOC. Our analyses provide an overview of the diversity and abundance of defence systems in this group, with 83,738 systems distributed by 2 to 33 within each assembly. Comparing PADLOC and DefenseFinder predictions showed that the most prevalent strategy is Restriction-Modification, but many ab

SUBMITTER: July E 

PROVIDER: S-EPMC11811056 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature