The Impact of Perioperative Radiotherapy on Disease-Specific Survival in Patients with Localized Retroperitoneal Liposarcoma: A Population-Based Propensity-Score Matched Analysis.

ABSTRACT:

Background

The impact of radiotherapy on the oncologic outcome of retroperitoneal liposarcoma (RPLS) remains controversial. The aim of this study was to evaluate the effect of radiotherapy on disease-specific survival (DSS) in a cohort of patients with RPLSs.

Methods

In this population-based, retrospective cohort study, patients with localized RPLSs who underwent surgical therapy were identified from the Surveillance, Epidemiology, and End Results-17 cancer registry program. After propensity-score matching for potential confounders, multivariable logistic and Cox regression analyses were used to examine factors associated with DSS and radiotherapy.

Results

From 2004 to 2020, 1692 patients with localized RPLS who underwent surgical therapy were identified (84.2%  White

SUBMITTER: Wilhelm A 

PROVIDER: S-EPMC11811447 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature