Donation after circulatory death transplantation: a systematic review and meta-analysis of outcomes and methods of donation.

ABSTRACT:

Background

Heart failure remains a significant cause of morbidity and mortality internationally. With significant disparities in supply and demand for donor organs and recipients, there has been a growing need to expand the donor pool. Donation after circulatory death (DCD) heart transplantation offers such a method, with ex-situ machine perfusion (ESMP) and thoracoabdominal normothermic reperfusion (NRP) offering two potential methods of procuring DCD organs. This systematic review and meta-analysis aims to evaluate the current literature and compare DCD with donation after brain death (DBD) as well as DCD methods of transplantation.

Methods

A systematic literature review was performed according to PRISMA guidelines. Primary outcomes were 30-day, 6- and 12-month survival, a

SUBMITTER: Jolliffe J 

PROVIDER: S-EPMC11811570 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature