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Cardiac transplantation in controlled donation after circulatory death: a meta-analysis of long-term survival using reconstructed time-to-event data.


ABSTRACT:

Background

Controlled donation after circulatory death (cDCD) allografts made up a small fraction of donor hearts available for transplant, however it is estimated this could increase to 30% in future years. The purpose of this systematic review and meta-analysis was to describe the largest and most up-to-date short- and long-term survival outcomes for cDCD cardiac transplantation.

Methods

Three electronic databases were selected to complete the initial literature search from inception of records until February 2024. Primary outcomes were short-term survival at 12 months, as well as long-term time-to-event survival data. These data were calculated using aggregated Kaplan-Meier curves according to established methods. The secondary outcomes were acute rejection and primary gr

SUBMITTER: Muston BT 

PROVIDER: S-EPMC11811572 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature