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Predictive value of ANE-SS combined with ferritin and DIC scores for mortality Risk in children with acute necrotizing encephalopathy.


ABSTRACT:

Background

Acute necrotizing encephalopathy (ANE) is a para-infectious neurological disorder with high mortality in children. There are limited studies evaluating predictive factors for mortality in ANE patients. This study aims to investigate the predictive value of independent risk factors and the ANE Severity Score (ANE-SS), combined with ferritin levels and Disseminated Intravascular Coagulation (DIC) scores, in assessing mortality risk in children with ANE.

Methods

We conducted a retrospective study of children with ANE in the pediatric intensive care unit of Beijing Children's Hospital from January 2016 to May 2024. The patients were divided into survival and non-survival groups, and clinical data were collected within 12 hours after admission. The predictive value of

SUBMITTER: Li F 

PROVIDER: S-EPMC11811582 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature