Management of coexisting patent foramen ovale and pulmonary arteriovenous malformation: a case report of sequential closure.

ABSTRACT:

Background

Concurrent patent foramen ovale (PFO) and pulmonary arteriovenous malformation (PAVM) are rare but can cause paradoxical embolism and platypnoea-orthodeoxia syndrome (POS).

Case summary

A 72-year-old female with embolic stroke history developed positional dyspnoea. Evaluation revealed right-to-left shunting through PFO and PAVM in the right middle lobe. Orthodeoxia was confirmed by 6% SpO₂ decrease upon position change. A staged approach was adopted: PFO closure with Amplatzer™ Occluder, followed by PAVM embolization 1 month later. Symptoms improved significantly post-procedure. No residual shunting or symptoms have been observed during the 2-year follow-up.

Discussion

This case emphasizes thorough evaluation in patients with cryptogenic stroke a

SUBMITTER: Yagasaki H 

PROVIDER: S-EPMC11811738 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature