Detection and quantification of pathogens in saliva of adolescents with cerebral palsy: a cross-sectional study.

ABSTRACT:

Background

Elevated levels of inflammatory mediators in saliva have been described in individuals with cerebral palsy (CP).

Objective

The aim of this study was to detect and quantify the pathogens Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum and Prevotella intermedia in the saliva of adolescents with CP.

Methods

This is a cross-sectional study with adolescents with CP to detect periodontopathogens from saliva samples. Initially, saliva was collected from the CP (n = 34) and control groups (n = 31), followed by the gingival index (GI) for distribution of the groups of individuals with CP and control with gingivitis (bleeding on probing ≥ 10%) and without gingivitis. Bacterial DNA was extracted from saliva

SUBMITTER: Yoshida RA 

PROVIDER: S-EPMC11811777 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature