Selectivity Effects of Hydrogen Acceptors and Catalyst Structures in Alcohol Oxidations Using (Cyclopentadienone)iron Tricarbonyl Compounds.

ABSTRACT: Oppenauer-type oxidations are catalyzed by air- and moisture-stable, sustainable, (cyclopentadienone)iron carbonyl compounds, but the substrate scope is limited due to the low reduction potential of acetone, which is the most commonly used hydrogen acceptor. We discovered that furfural, an aldehyde derived from cellulosic biomass, is an effective hydrogen acceptor with this class of catalysts. In general, reactions using furfural as the hydrogen acceptor led to higher isolated yields of ketones and aldehydes compared to those using acetone. Importantly, primary benzylic and allylic alcohols─typically a challenging class of alcohols to oxidize with these catalysts─could be oxidized. The selectivity for primary vs secondary alcohol oxidation with (cyclopentadienone)iron carbonyl catalysts wa

SUBMITTER: Hempel M 

PROVIDER: S-EPMC11812019 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature