Dynamics of tumor evolution after Gamma Knife radiosurgery for sporadic vestibular schwannoma: Defining volumetric patterns characterizing individual trajectory.

ABSTRACT:

Background

The definition of tumor control and treatment failure after Gamma Knife radiosurgery (GKRS) for vestibular schwannoma (VS) is still debated. The lack of knowledge on the dynamics of tumor evolution can lead to misinterpretation and subsequent inappropriate second treatment. The aim of this study was to evaluate the post-GKRS dynamics of the evolution of tumor volume and characterize volumetric patterns.

Methods

We included patients with sporadic VS treated by GKRS with an MRI follow-up of a minimum of 3 years. A clustering was performed in 2 steps: Definition of the patterns of evolution based on a subset of patients with the most comprehensive follow-up, and then the assignment of the remaining patients on a best-fit basis. The minimum length of follow-up was ass

SUBMITTER: Balossier A 

PROVIDER: S-EPMC11812029 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature