Household air pollution and epigenetic aging in Xuanwei, China.

ABSTRACT:

Background

Household air pollution (HAP) from indoor combustion of solid fuel is a global health burden linked to lung cancer. In Xuanwei, China, lung cancer rate for nonsmoking women is among the highest in the world and largely attributed to high levels of polycyclic aromatic hydrocarbons (PAHs) that are produced from combustion of smoky (bituminous) coal used for cooking and heating. Epigenetic age acceleration (EAA), a DNA methylation-based biomarker of aging, has been shown to be highly correlated with biological processes underlying the susceptibility of age-related diseases. We aim to assess the association between HAP exposure and EAA.

Methods

We analyzed data from 106 never-smoking women from Xuanwei, China. Information on fuel type was collected using a questionnai

SUBMITTER: Blechter B 

PROVIDER: S-EPMC11812304 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature