Biomarkers in coronary artery disease: systematic review and meta-analysis.

ABSTRACT:

Introduction

Little information exists regarding the detection of early coronary heart disease protein biomarkers. The aim of this study was to investigate several potential candidates.

Methods

Systematic review was carried out followed by meta-analysis.

Results

The standardized mean difference (95% confidence intervals) for each comparison was: Troponins 2.31 (1.18, 3.4), iL-6 1.3 (0.8, 1.81), fibrinogen 1.55 (1.16, 1.94), NT-proBNP 1.05 (0.72, 1.38), lipoprotein a 0.75 (0.48, 1.03) osteoprotegerin 0.92 (0.23, 1.62), VCAM-1 1.53 (0.87, 2.18), pentraxin 3 0.87 (-0.13, 1.87), PAI-1 2.51 (-0.65, 5.66) MMP9 1.25 (0.36, 2.14), MCP-1 1.99 (1.12, 2.85) and adiponectin -1.11 (-1.49, -0.73).

Conclusion

Multiple biomarkers that could potentially be used for the early de

SUBMITTER: King N 

PROVIDER: S-EPMC11812396 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature