Childhood trajectories of emotional and behavioral difficulties are related to polygenic liability for mood and anxiety disorders.

ABSTRACT:

Background

Symptoms related to mood and anxiety disorders (emotional disorders) often present in childhood and adolescence. Some of the genetic liability for mental disorders, and emotional and behavioral difficulties seems to be shared. Yet, it is unclear how genetic liability for emotional disorders and related traits influence trajectories of childhood behavioral and emotional difficulties, and if specific developmental patterns are associated with higher genetic liability for these disorders.

Methods

This study uses data from a genotyped sample of children (n = 54,839) from the Norwegian Mother, Father, and Child Cohort Study (MoBa). We use latent growth models (1.5-5 years) and latent profile analyses (1.5-8 years) to quantify childhood trajectories and profiles of emot

SUBMITTER: Bakken NR 

PROVIDER: S-EPMC11812494 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature