Economic evaluation of newborn deafness gene screening as a public health intervention in China: a modelling study.

ABSTRACT:

Background

While global newborn hearing screening programmes (NHSP) are far from the optimal level, the combined hearing and genetic screening has emerged as an innovative approach of early healthcare interventions. There is a clear need for economic evaluation to establish whether newborn deafness gene screening (NDGS), currently mandated by many cities in China, is a good investment.

Methods

A decision-tree model was constructed to simulate a hypothetical 10-million Chinese newborn cohort over a lifetime with three strategies: (1) no screening, (2) NHSP (standard screening) and (3) NHSP+NDGS (combined screening). The presence of permanent congenital hearing loss (PCHL) and genetic mutation were assigned at birth and held constant for all strategies. Input parameters were o

SUBMITTER: Shu JT 

PROVIDER: S-EPMC11812888 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature