Effects of exercise on high-density lipoprotein levels in middle-aged and older individuals: A systematic review and meta-analysis.

ABSTRACT:

Background

This study aimed to perform a systematic review and meta-analysis of randomized controlled trials investigating the effect of exercise on high-density lipoprotein (HDL) levels in middle-aged and older individuals.

Methods

A systematic search was conducted in PubMed, Web of Science, and EMBASE, including meta-analyses of randomized controlled trials that investigated the effects of exercise on HDL-C levels in middle-aged and older individuals.

Results

Forty-two trials were analyzed. We found that exercise had a significant effect on HDL cholesterol levels (standard mean difference [95% confidence interval] = 0.22 [0.09-0.35], Z = 3.28, P = .001, I2 = 54%), and the heterogeneity across the studies was significant and high. After subgroup analysis, we found th

SUBMITTER: Liang L 

PROVIDER: S-EPMC11813029 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature