The efficacy of Sijunzi on immune function in patients with gastrointestinal cancers after surgery: Integrating systematic review and network pharmacology.

ABSTRACT:

Background

Patients with gastrointestinal cancer often have impaired immune function after surgery. This study aimed to assess the efficacy of Sijunzi decoction (SJZD) on immune function in patients with gastrointestinal cancers after surgery.

Methods

The electronic databases, including CNKI, Wanfang, SinoMed, Weipu, PubMed, Web of Science, EMBASE, and Cochrane databases were retrieved (March 1, 2024), and the randomized controlled trials (RCTs) that met the criteria were included. Methodologic quality assessment of RCTs was performed using the Cochrane risk of bias tool. The data of RCTs were acquired and analyzed by meta-analysis by Review Manager 5.3, and the quality of the evidence followed the Grading of Recommendations, Assessment, Development and Evaluations approach.

SUBMITTER: Wu Z 

PROVIDER: S-EPMC11813061 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature