Risk assessment of antibiotic residues and resistance profile of E. coli in typical rivers of Sichuan, China.

ABSTRACT: The presence and distribution of antibiotics and antibiotic resistance genes (ARGs) in rivers have attracted significant global concern. However, research on the contamination of typical rivers in Sichuan Province, China, remains limited. This study aimed to assess the residual levels of antibiotics across 42 national and provincial monitoring sites in nine rivers within Sichuan using UPLC-MS/MS. Ecological risk levels were evaluated through established risk assessment methods, and antibiotic resistance in Escherichia coli(E.coli) isolated from these waters was determined using the Kirby-Bauer disk diffusion method. Additionally, redundancy analysis (RDA) was conducted to explore the impact of residual antibiotics on the microbial community structure in the Minjiang River basin. Antibiotic

SUBMITTER: Sha J 

PROVIDER: S-EPMC11813091 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature