Clinical Practice Guidelines for Dementia: Recommendations for Cholinesterase Inhibitors and Memantine.

ABSTRACT:

Background and purpose

This clinical practice guideline provides evidence-based recommendations for treatment of dementia, focusing on cholinesterase inhibitors and N-methyl-D-aspartate (NMDA) receptor antagonists for Alzheimer's disease (AD) and other types of dementia.

Methods

Using the Population, Intervention, Comparison, Outcomes (PICO) framework, we developed key clinical questions and conducted systematic literature reviews. A multidisciplinary panel of experts, organized by the Korean Dementia Association, evaluated randomized controlled trials and observational studies. Recommendations were graded for evidence quality and strength using Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology.

Results

Three main recommendations

SUBMITTER: Kim Y 

PROVIDER: S-EPMC11813556 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature