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Neuroimaging Findings in Nondemented Frail Individuals: A Systematic Review.


ABSTRACT:

Background

Frailty is a chronic condition characterised by the progressive decline of multiple physiological functions. There is a critical need to investigate neuroimaging findings in nondemented frail individuals to better understand the underlying mechanisms and implications of frailty on brain health. This paper is aimed at reviewing neuroimaging studies assessing brain changes in nondemented frail individuals to understand the neuropsychological basis of frailty.

Methods

A systematic review was conducted on studies focusing on neuroimaging modalities in frailty, including MRI, fMRI, DTI and PET. The review was based on PRISMA instructions and a two-step screening process. The studies evaluating neuroimaging findings of nondemented frail individuals, regardless of public

SUBMITTER: Harandi H 

PROVIDER: S-EPMC11813630 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature