Jiawei Suanzaoren decoction for the treatment of perimenopausal insomnia: clinical observation and experimental study.

ABSTRACT:

Background

Traditional Chinese medicine has a good clinical therapeutic effect on perimenopausal insomnia, Jiawei Suanzaoren Tang (JW-SZRT) has a significant therapeutic effect on people with yin deficiency and fire excess type insomnia.

Method

Firstly, 80 cases of perimenopausal yin deficiency and fire excess type insomnia were included in the study. The treatment group was treated with Jiawei Suanzaoren decoction, while the control group was treated with lorazepam for 4 weeks. The study observed and compared the Pittsburgh Sleep Quality Index (PSQI), Kupperman score, Polysomnography (PSG) and sex hormone levels of two groups before and after treatment. Secondly, we also conducted network pharmacology analysis and mechanism research. We first searched public databases for t

SUBMITTER: Chen LQ 

PROVIDER: S-EPMC11813739 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature