Global, regional, and national burden of children and adolescents with acute lymphoblastic leukemia from 1990 to 2021: a systematic analysis for the global burden of disease study 2021.

ABSTRACT:

Background

Acute lymphoblastic leukemia (ALL) is a common cancer in children and adolescents, severely affecting their survival and health. With the discovery of new drugs and improved treatment options, the survival rate of ALL in children and adolescents has improved significantly.

Methods

We used the GBD (global burden of disease) database to collect patients aged 0-19 years (0-5 years, 5-9 years, 10-14 years, 15-19 years) diagnosed with ALL between 1990 and 2021. Disease status and change were analyzed by learning about the prevalence, death, incidence, DALYs (disability-adjusted life years), percentage change, and the estimated annual percentage change (EAPC).

Results

In 2021, there were 53,485 new cases of childhood and adolescent ALL, 23,991 deaths, and an esti

SUBMITTER: Wang L 

PROVIDER: S-EPMC11813771 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature