Harmonization of the fastest and densest responses reflects humanlike reaction time in mice.

ABSTRACT:

Introduction

Reaction time (RT) is important for evaluating delayed latency in behavior. Unlike humans, whose RT usually reflects a one-to-one stimulus-response relationship, the RT of animals can show two peaks representing the fastest and densest responses in the response distribution due to multiple responses per trial and can be further delayed depending on stimulus duration.

Methods

Stimulus duration was controlled to investigate whether these two peak latencies align to form a single RT. Sound cues lasting 10, 5, and 2 s, each associated with a food reward of condensed milk, were tested in three groups of 24 mice using delay conditioning paradigm. The frequency and latency of responses, along with basic indices such as accuracy, were analyzed.

Results

In delay c

SUBMITTER: Kim CH 

PROVIDER: S-EPMC11813871 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature