An expert perspective on diversity-oriented standards for assessing sex and gender in clinical research.

ABSTRACT:

Introduction

Randomized controlled trials require diverse patient groups to ensure broad applicability of results. However, gender minorities are often not included, which affects the generalizability and equity of healthcare outcomes. Inclusive research must consider the diversity of sex and gender to eliminate inequalities and improve health outcomes.

Methods

A two-stage expert survey was conducted using a self-developed questionnaire in which the constructs of sex, gender, and gender expression were considered. Experts rated the importance and practicality of assessing these concepts in clinical trials and evaluated terms for suitability and comprehension. In addition, existing definitions were refined. Consensus was defined as 70% agreement or disagreement.

Results

SUBMITTER: Hambruch HR 

PROVIDER: S-EPMC11814446 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature