Exploring the Joint Association Between Agrichemical Mixtures and Pediatric Cancer.

ABSTRACT: Nebraska's age-adjusted incidence rates for childhood cancers are among the highest in the US. Previous studies indicated associations between agrichemical exposures (atrazine and nitrates) and pediatric cancer rate, assuming single pollutant exposure. We evaluated the joint association between the agricultural mixture and pediatric cancer. Agrichemical exposures at a county scale were quantified using the USGS Pesticide National Synthesis Project for frequently applied pesticides from 1992 to 2014 in 93 Nebraska counties. Outcomes were quantified using pediatric cancer diagnosed among children <20 years of age (1992-2014) from the Nebraska cancer registry. We adjusted for social vulnerability factors such as race, income, employment, and access to care. The associations between 32 agriche

SUBMITTER: Taiba J 

PROVIDER: S-EPMC11815328 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature