Association of race and ethnicity with mortality in adults with SLE: a systematic literature review and meta-analysis.

ABSTRACT:

Objectives

Ethnicity and health outcomes are intrinsically interrelated, although mechanisms are complex. SLE is a disease with higher incidence in Asian, Black, Hispanic and Indigenous populations than in White populations. SLE is associated with premature mortality, but it is unclear if ethnicity impacts on health outcomes as studies are frequently underpowered. We aimed to describe the association between SLE and mortality across different racial and ethnic groups using meta-analysis.

Methods

We identified studies of adults with SLE that reported mortality, stratified by racial and ethnic group, through a systematic literature review. We used a pairwise meta-analysis to determine the pooled odds ratio (OR) of death for those from underserved groups compared with those of

SUBMITTER: Patel S 

PROVIDER: S-EPMC11815449 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature