Chemical degradation as an enabling pathway to polymersome functionalization.

ABSTRACT: Readiness and the ability to functionalize are the fundamental features of natural living systems. Understanding the chemical roots of functionalization is a basic quest for the generation of new materials in the laboratory and chemistry-based natural-life-mimicking artificial or synthetic living systems. Using polymerization-induced self-assembly (PISA) and starting from a homogeneous aqueous blend of a few strictly non-biochemical compounds, it is possible to create amphiphiles that can self-boot into submicron supramolecular objects (micelles). These micelles under the control of chemistry can undergo (1) morphological evolution into giant polymersomes and (2) exhibit growth-implosion cycles accompanied by (3) vesicle self-reproduction and population growth. We call the physico-chemical

SUBMITTER: Lin C 

PROVIDER: S-EPMC11815554 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature