Safer and targeted use of antipsychotics in youth: an embedded, pragmatic randomized trial.

ABSTRACT:

Background

Antipsychotic medications (AP) are inappropriately prescribed to young people. The goal of this pragmatic trial was to test a four-component approach to improved targeting of antipsychotic prescribing to people aged ≥3 and <18 years.

Methods

Clinicians in four health systems were cluster randomized by the number of previous AP orders and service line - specialty mental health and all others. Intervention arm clinicians received a best practice alert and child psychiatrist consultation and feedback. Families received system navigation and expedited access to psychotherapy. Primary outcomes were total days' supply of AP medication and proportion of youth with any AP supply at 6 months. We estimated the log-odds of AP use at 6 months and the relative rate of AP over

SUBMITTER: Penfold RB 

PROVIDER: S-EPMC11815570 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature