Characteristics and Outcomes of T1a Renal Cell Carcinoma Presenting with Metastasis.

ABSTRACT:

Objectives

The incidence of renal cell carcinoma (RCC) has been rising, largely due to increased incidental detection from widespread imaging. Although synchronous distant metastasis (SM) with a primary renal tumor measuring <4 cm (cT1a) is uncommon, its presence may influence survival outcomes and the utility of cytoreductive nephrectomy. We sought to investigate clinical characteristics, metastatic patterns, treatments, and survival outcomes of patients with T1a RCC.

Methods

All patients aged ≥18 years diagnosed with RCC between 2004 and 2019 were extracted from the National Cancer Database. The Cochran-Armitage test was used for trend analysis, while multivariable analyses were conducted to identify variables associated with SM and to assess the impact of cytoreductive su

SUBMITTER: Wang L 

PROVIDER: S-EPMC11815727 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature