Rapid, Highly Sustainable Ring-Opening Polymerization via Resonant Acoustic Mixing.

ABSTRACT: Reported herein is the first combination of resonant acoustic mixing (RAM) and controlled ring-opening polymerization (ROP) to deliver fully sustainable, end-functionalized, biodegradable polymers via a manufacturing route with a much-reduced environmental impact. This includes the successful use of agriculturally sourced functionalized initiators (terpene alcohols) in ROP synthesis of cyclic esters to generate an array of novel, biodegradable polyesters applicable to numerous biomedical applications, such as drug delivery. Furthermore, RAM was utilized as a novel mixing technique, resulting in a synthetic process that was conducted: (a) with minimal use of toxic, flammable, costly, and environmentally detrimental solvents, (b) in the absence of organometallic catalysts, and (c) with signi

SUBMITTER: Fowler HR 

PROVIDER: S-EPMC11816011 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature