Development and validation of a population-based risk algorithm for premature mortality in Canada: the Premature Mortality Population Risk Tool (PreMPoRT).

ABSTRACT:

Introduction

To develop and validate the Premature Mortality Population Risk Tool (PreMPoRT), a population-based risk algorithm that predicts the 5-year incidence of premature mortality among the Canadian adult population.

Methods

Retrospective cohort analysis used six cycles of the Canadian Community Health Survey linked to the Canadian Vital Statistics Database (2000-2017). The cohort comprised 500 870 adults (18-74 years). Predictors included sociodemographic factors, self-perceived measures, health behaviours and chronic conditions. Three models (minimal, primary and full) were developed. PreMPoRT was internally validated using a split set approach and externally validated across three hold-out cycles. Performance was assessed based on predictive accuracy, discrimination

SUBMITTER: O'Neill M 

PROVIDER: S-EPMC11816297 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature