Psychiatric disorders and following risk of chronic kidney disease: a prospective cohort study from UK Biobank.

ABSTRACT:

Background

Psychiatric disorders have been reported to influence many health outcomes, but evidence about their impact on chronic kidney disease (CKD) has not been fully explored, as well as possible mechanisms implicated are still unclear.

Methods

Four hundred forty-one thousand eight hundred ninety-three participants from UK Biobank were included in this study. To assess the association between psychiatric disorders mainly including depression, anxiety, stress-related disorders, substance misuse as well as psychotic disorder, and CKD, a Cox regression model using age as the underlying time scale was employed. This approach considers the age progression of participants from the beginning to the end of the study as the elapsed time. Flexible nonparametric smoothing model was

SUBMITTER: Li H 

PROVIDER: S-EPMC11816523 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature