The first-trimester triglyceride glucose-body mass index is a valuable predictor for adverse pregnancy outcomes.

ABSTRACT:

Background

Although insulin resistance has been associated with unfavorable pregnancy outcomes, the ability of non-insulin-based insulin resistance indicators to predict adverse pregnancy outcomes has yet to be thoroughly understood. The study aims to investigate the association and predictability of triglyceride glucose-body mass index (TyG-BMI), a biomarker of non-insulin-based insulin resistance, with the risks of adverse pregnancy outcomes.

Method

The retrospective study included 1,136 subjects. Group-based trajectory modeling (GBTM) was employed to identify the TyG-BMI index trajectory. Logistic regression, restricted cubic spline (RCS) regression, and subgroup analysis were used to assess the association between the TyG-BMI index trajectory and the first-trimester TyG-

SUBMITTER: Meng Z 

PROVIDER: S-EPMC11816746 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature