Stroke and myocardial infarction with contemporary hormonal contraception: real-world, nationwide, prospective cohort study.

ABSTRACT:

Objective

To evaluate the association between contemporary hormonal contraceptive use and the risk of incident ischaemic stroke and myocardial infarction.

Design

Real-world, nationwide, prospective cohort study.

Setting

Denmark, by use of national registries.

Participants

All women aged 15-49 years residing in Denmark between 1996 and 2021, with no history of arterial or venous thrombosis, antipsychotics use, cancer, thrombophilia, liver disease, kidney disease, polycystic ovary syndrome, endometriosis, infertility treatment, hormone therapy use, oophorectomy, and hysterectomy.

Main outcome measures

First time diagnosis of ischaemic stroke or myocardial infarction at discharge.

Results

Among 2 025 691 women followed up for 22 209 697 person years,

SUBMITTER: Yonis H 

PROVIDER: S-EPMC11816856 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature