Research priorities to support typhoid conjugate vaccine decision-making in India: evidence assessment and stakeholder survey.

ABSTRACT:

Background

India has a high typhoid fever burden. In 2022, the National Technical Advisory Group on Immunisation recommended introducing typhoid conjugate vaccine (TCV) into the Universal Immunisation Programme. Our study aims to identify research priorities to support ongoing TCV decision-making in India.

Methods

We identified 45 evidence factors for TCV decision-making in India by adapting WHO's Evidence-to-Recommendation framework. We assigned an evidence gap score for each evidence factor from 0 (low) to 4 (high) based on the availability and sufficiency, quality, breadth and applicability of evidence identified in a literature review (end date 30 November 2023). We assigned each evidence factor an importance score based on the results of an online survey conducted among

SUBMITTER: Mogasale VV 

PROVIDER: S-EPMC11816874 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature