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Effect of liberal glucose control on critically ill patients: a systematic review and meta-analysis.


ABSTRACT:

Background

Most current guideline statements support some level of unrestricted glycemic management in critically ill adult patients. Nevertheless, the effectiveness of liberal glucose control is currently not well-supported by evidence. Therefore, our objective is to investigate the influence of liberal glucose control (> 180 mg/dl) on critically ill patients in the intensive care unit (ICU).

Methods

Until November 23, 2023, English language literature was thoroughly and systematically searched through multiple databases, including PubMed, Embase, Cochrane Library, and Web of Science. Our primary endpoints of interest were the occurrence of hypoglycemia, mortality in the ICU, and mortality during hospitalization. In addition, our secondary outcomes comprised of 90-day morta

SUBMITTER: Ma J 

PROVIDER: S-EPMC11817051 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature