The new definition of metabolic syndrome including hyperuricemia improves its prognostic value: results from NHANES database.

ABSTRACT:

Background

Metabolic syndrome (MetS) is a significant global health issue that is strongly associated with an increased risk of cardiovascular disease (CVD). While MetS was initially proposed to identify more high-risk individuals and facilitate early management, hyperuricemia has not yet been included in its definition, despite its strong association with MetS. This study aims to explore the prognostic value of incorporating hyperuricemia into the definition of MetS.

Methods

Data derived from the National Health and Nutrition Examination Survey (NHANES) conducted between 1999 and 2018 were analyzed. The old version of MetS (MetS_old) aligned with NCEP-ATP III criteria, whereas the new version of MetS (MetS_new) included hyperuricemia as a sixth criterion

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC11817069 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature