Prognostic role of geriatric nutritional risk index (GNRI) and controlling nutritional status (CONUT) on outcomes in patients with head and neck cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Malnutrition is a common comorbidity in patients with head and neck cancer (HNC), significantly impacting survival rates. The Geriatric Nutritional Risk Index (GNRI) and the Controlling Nutritional Status (CONUT) score are tools used to assess the nutritional status, yet their prognostic value in HNC remains to be fully established.

Methods

We performed a systematic review and meta-analysis, adhering to PRISMA guidelines, to evaluate the prognostic significance of GNRI and CONUT on survival outcomes in patients with HNC. Relevant studies up to March 2024 were identified through comprehensive searches of PubMed, EMBASE, and Cochrane CENTRAL databases. The quality of each included study was assessed using the Newcastle-Ottawa Scale.

Results

Seventeen studies

SUBMITTER: Huang YC 

PROVIDER: S-EPMC11817134 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature