Efficient degradation of neomycin by Bacillus velezensis and Cupriavidus basilensis isolated from mangrove soil and pharmaceutical wastewater.

ABSTRACT: Neomycin, an aminoglycoside antibiotic, is widely utilized for veterinary medicine in disease prevention. Biodegradation is a key pathway for the removal of neomycin from the environment. To date, only the white-rot fungus Trametes versicolor and the ericoid mycorrhizal fungus Rhizoscyphus ericae have been documented to efficiently degrade neomycin. However, no bacterial species with neomycin-degrading capabilities have been reported, underscoring a significant gap in microbial research related to neomycin remediation. In this study, Cupriavidus basilensis and Bacillus velezensis were isolated from pharmaceutical wastewater and neomycin-free mangrove soil through enrichment culture and gradual acclimatization, respectively. These isolates demonstrated neomycin d

SUBMITTER: Yang Q 

PROVIDER: S-EPMC11817266 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature