"Omics" and Postmortem Interval Estimation: A Systematic Review.

ABSTRACT: Postmortem interval (PMI) estimation is a challenge of utmost importance in forensic daily practice. Traditional methods face limitations in accuracy and reliability, particularly for advanced decomposition stages. Recent advances in "omics" sciences, providing a holistic view of postmortem biochemical changes, offer promising avenues for overcoming these challenges. This systematic review aims at investigating the role of mass-spectrometry-based "omics" approaches in PMI estimation to elucidate molecular mechanisms underlying predictable time-dependent biochemical alterations occurring after death. A systematic search was performed, adhering to PRISMA guidelines, through "free-text" protocols in the databases PubMed, SCOPUS and Web of Science. The inclusion criteria were as follows: exper

SUBMITTER: Secco L 

PROVIDER: S-EPMC11817326 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature