Wolbachia enhances the survival of Drosophila infected with fungal pathogens.

ABSTRACT:

Background

Wolbachia bacteria of arthropods are at the forefront of basic and translational research on multipartite host-symbiont-pathogen interactions. These vertically transmitted microbes are the most widespread endosymbionts on the planet due to factors including host reproductive manipulation and fitness benefits. Importantly, some strains of Wolbachia can inhibit viral pathogenesis within and between arthropod hosts. Mosquitoes carrying the wMel Wolbachia strain of Drosophila melanogaster have a greatly reduced capacity to spread viruses like dengue and Zika to humans. While significant research efforts have focused on viruses, relatively little attention has been given to Wolbachia-fungal interactions despite the ubiquity of fungal entomopathogens in nature.

Results

SUBMITTER: Perlmutter JI 

PROVIDER: S-EPMC11817339 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature