The Molecular Mechanism of <i>Clock</i> in Thermal Adaptation of Two Congeneric Oyster Species.

ABSTRACT: Clock genes regulate physiological and metabolic processes by responding to changes in environmental light and temperature, and genetic variations in these genes may facilitate environmental adaptation, offering opportunities for resilience to climate change. However, the genetic and molecular mechanisms remain unclear in marine organisms. In this study, we investigated the role of a key clock gene, the circadian locomotor output cycles kaput (Clock), in thermal adaptation using DNA affinity purification sequencing (DAP-Seq) and RNA interference (RNAi)-based transcriptome analysis. In cold-adapted Crassostrea gigas and warm-adapted Crassostrea angulata, Clock was subject to environmental selection and exhibited contrasting expression patterns. The transcriptome

SUBMITTER: Jiang Z 

PROVIDER: S-EPMC11817431 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature