Correlations Between MR Apparent Diffusion Coefficients and PET Standard Uptake Values in Simultaneous MR-PET Imaging of Prostate Cancer.

ABSTRACT: This study evaluated the hypothesis that ⁶⁸Ga-PSMA-11 PET SUV, obtained via an advanced DL approach, correlates better with MR ADC maps than values from conventional PET-MR. Additionally, we aimed to identify the optimal SUV threshold for maximum correlation with ADC values. A cohort of 32 prostate cancer patients underwent CT and corresponding PET-MR imaging. The dataset underwent K-fold cross-validation, dividing it into four folds. In each fold, 24 patients were used for training, and 8 for validation to create DL models. ADC maps from 27 out of 32 patients were successfully aligned with T2 images for detailed analysis, revealing an inverse correlation (ρ = -0.20 to -0.51) between ADC and SUV values in prostate cancer zones. Statistically significant differences in mean SUV v

SUBMITTER: Pozaruk A 

PROVIDER: S-EPMC11817574 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature