Possible Use of Body Surface Area Value for Estimating Skeletal Muscle Mass in Chronic Liver Disease.

ABSTRACT: Background/Objectives: Sarcopenia is an important clinical feature of patients with chronic liver disease (CLD). However, special devices are required to determine skeletal muscle mass. We evaluated the usefulness of body surface area (BSA) for estimating muscle mass and diagnosing sarcopenia in patients with CLD. Methods: We retrospectively studied 1889 Japanese patients with CLD who underwent bioimpedance analysis (BIA) (training cohort, n = 983; validation cohort, n = 906). The optimal cutoff values for predicting low skeletal muscle mass index (SMI) were determined using ROC analysis. We also assessed 1229 patients whose BSA and grip strength (GS) data were obtained on the same day and evaluated the diagnostic performance of the determined cutoff values of BSA for the dia

SUBMITTER: Yoh K 

PROVIDER: S-EPMC11817660 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature